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Found 4 Enz. Inhib. hit(s) with Target = 'Adenosine receptor A2b' and Ligand = 'BDBM551718'
TargetAdenosine receptor A2b(Homo sapiens (Human))
Merck Sharp & Dohme

US Patent
LigandPNGBDBM551718((R or S)-3-(4-((2S,5R or 2R,5S)-5-(5-amino-9-fluor...)
Affinity DataIC50:  4.5nMAssay Description:The ability of compounds to antagonize human A2A and A2B adenosine receptors was determined using a kit to measure changes in intracellular cyclic AM...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetAdenosine receptor A2b(Homo sapiens (Human))
Merck Sharp & Dohme

US Patent
LigandPNGBDBM551718((R or S)-3-(4-((2S,5R or 2R,5S)-5-(5-amino-9-fluor...)
Affinity DataIC50:  14.3nMAssay Description:The ability of compounds to antagonize human A2A and A2B adenosine receptors was determined using a kit to measure changes in intracellular cyclic AM...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetAdenosine receptor A2b(Homo sapiens (Human))
Merck Sharp & Dohme

US Patent
LigandPNGBDBM551718((R or S)-3-(4-((2S,5R or 2R,5S)-5-(5-amino-9-fluor...)
Affinity DataIC50:  580nMAssay Description:The ability of compounds to antagonize human A2A and A2B adenosine receptors was determined using a kit to measure changes in intracellular cyclic AM...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetAdenosine receptor A2b(Homo sapiens (Human))
Merck Sharp & Dohme

US Patent
LigandPNGBDBM551718((R or S)-3-(4-((2S,5R or 2R,5S)-5-(5-amino-9-fluor...)
Affinity DataIC50:  1.22E+3nMAssay Description:The ability of compounds to antagonize human A2A and A2B adenosine receptors was determined using a kit to measure changes in intracellular cyclic AM...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent