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Found 3 Enz. Inhib. hit(s) with Target = 'Adenosylhomocysteinase' and Ligand = 'BDBM50018500'
TargetAdenosylhomocysteinase(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50018500(CHEMBL419393)
Affinity DataIC50:  195nMAssay Description:Inhibition of recombinant human AHCY using SAH as substrate assessed as formation of homocysteine after 10 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosylhomocysteinase(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50018500(CHEMBL419393)
Affinity DataIC50:  939nMAssay Description:Inhibition of AHCY in human SH-SY5Y cells assessed as formation of homocysteine after 48 hrs by HPLC analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosylhomocysteinase(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50018500(CHEMBL419393)
Affinity DataIC50: >3.54E+4nMAssay Description:Inhibitory effect against S-adenosyl-L-homocysteine hydrolase of rabbit erythrocyte.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed