Compile Data Set for Download or QSAR
Report error Found 2 Enz. Inhib. hit(s) with Target = 'Aldo-keto reductase family 1 member A1' and Ligand = 'BDBM16452'
TargetAldo-keto reductase family 1 member A1(Human)
Gifu Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM16452((4-oxo-3-{[5-(trifluoromethyl)-1,3-benzothiazol-2-...)
Affinity DataIC50: 2.70E+3nMAssay Description:Inhibition of N-terminal 6His-tagged human aldehyde reductase expressed in Escherichia coli BL21(DE3) mediated D-glucuronate reductionMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/21/2010
Entry Details Article
PubMed
TargetAldo-keto reductase family 1 member A1(Human)
Gifu Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM16452((4-oxo-3-{[5-(trifluoromethyl)-1,3-benzothiazol-2-...)
Affinity DataIC50: 3.86E+4nMAssay Description:The activity of the test enzyme was determined spectrophotometrically by monitoring the change in absorbance at 340 nm, which is due to the disappear...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/2/2007
Entry Details Article
PubMed