Found 4 Enz. Inhib. hit(s) with Target = 'Aldo-keto reductase family 1 member A1' and Ligand = 'BDBM50049730'
TargetAldo-keto reductase family 1 member A1(Rattus norvegicus)
Nippon Zoki Pharmaceutical
Curated by ChEMBL
Nippon Zoki Pharmaceutical
Curated by ChEMBL
Affinity DataIC50: 1.50E+3nMAssay Description:In vitro inhibitory activity against rat kidney aldehyde reductase(ALR).More data for this Ligand-Target Pair
Affinity DataIC50: 1.50E+3nMAssay Description:Selectivity ratio measured as the IC50 ratio of aldehyde/aldose reductase valuesChecked by AuthorMore data for this Ligand-Target Pair
TargetAldo-keto reductase family 1 member A1(Homo sapiens (Human))
University Of Toyama
Curated by ChEMBL
University Of Toyama
Curated by ChEMBL
Affinity DataIC50: 2.60E+3nMAssay Description:Inhibition of human recombinant AKR1A1 expressed in Escherichia coli BL21 cells using D-glucuronate as substrate by spectrophotometryMore data for this Ligand-Target Pair
TargetAldo-keto reductase family 1 member A1(Homo sapiens (Human))
University Of Toyama
Curated by ChEMBL
University Of Toyama
Curated by ChEMBL
Affinity DataIC50: 2.60E+3nMAssay Description:Inhibition of N-terminal 6His-tagged human aldehyde reductase expressed in Escherichia coli BL21(DE3) mediated D-glucuronate reductionMore data for this Ligand-Target Pair