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Found 4 Enz. Inhib. hit(s) with Target = 'Aldo-keto reductase family 1 member B1' and Ligand = 'BDBM50146187'
TargetAldo-keto reductase family 1 member B1(Rattus norvegicus)
Aristotle University Of Thessaloniki

Curated by ChEMBL
LigandPNGBDBM50146187((3-Benzoyl-pyrrol-1-yl)-acetic acid | 2-(3-benzoyl...)
Affinity DataIC50:  1.97E+3nMAssay Description:In vitro inhibitory activity of compound against rat lens aldose reductaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAldo-keto reductase family 1 member B1(Rattus norvegicus)
Aristotle University Of Thessaloniki

Curated by ChEMBL
LigandPNGBDBM50146187((3-Benzoyl-pyrrol-1-yl)-acetic acid | 2-(3-benzoyl...)
Affinity DataIC50:  1.97E+3nMAssay Description:Inhibition of aldose reductase in Fischer-344 rat lens homogenate by spectrometric analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAldo-keto reductase family 1 member B1(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research And Development

Curated by ChEMBL
LigandPNGBDBM50146187((3-Benzoyl-pyrrol-1-yl)-acetic acid | 2-(3-benzoyl...)
Affinity DataIC50:  2.40E+3nMAssay Description:Inhibition of aldose reductaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAldo-keto reductase family 1 member B1(Rattus norvegicus)
Aristotle University Of Thessaloniki

Curated by ChEMBL
LigandPNGBDBM50146187((3-Benzoyl-pyrrol-1-yl)-acetic acid | 2-(3-benzoyl...)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of partially purified Fischer-344 rat kidney ALR1 using D,L-glycuronate as substrate assessed as NADPH consumption by spectrophotometryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed