Found 3 Enz. Inhib. hit(s) with Target = 'Aldo-keto reductase family 1 member B10' and Ligand = 'BDBM16452' TargetAldo-keto reductase family 1 member B10(Homo sapiens (Human))
Institut De Ge??Ne??Tique Et De Biologie Mole??Culaire Et Cellulaire
Institut De Ge??Ne??Tique Et De Biologie Mole??Culaire Et Cellulaire
Affinity DataIC50: 620nMpH: 7.0Assay Description:The IC50-activity assays were carried out on the basis of the quantification of the NADPH consumption that takes place when the enzyme catalyzes the ...More data for this Ligand-Target Pair
3D Structure (crystal)TargetAldo-keto reductase family 1 member B10(Homo sapiens (Human))
Institut De Ge??Ne??Tique Et De Biologie Mole??Culaire Et Cellulaire
Institut De Ge??Ne??Tique Et De Biologie Mole??Culaire Et Cellulaire
Affinity DataIC50: 620nMAssay Description:Inhibition of reductase activity of N-terminal 6His-tagged AKR1B10 expressed in Escherichia coli BL21(DE3) assessed as inhibition of NADPH linked pyr...More data for this Ligand-Target Pair
TargetAldo-keto reductase family 1 member B10(Homo sapiens (Human))
Institut De Ge??Ne??Tique Et De Biologie Mole??Culaire Et Cellulaire
Institut De Ge??Ne??Tique Et De Biologie Mole??Culaire Et Cellulaire
Affinity DataIC50: 2.36E+3nMAssay Description:Inhibition of recombinant AKR1B10 assessed as NADP+ dependent reduction of DL-glyceraldehyde by fluorescence assayMore data for this Ligand-Target Pair
