Compile Data Set for Download or QSAR
Report error Found 4 Enz. Inhib. hit(s) with Target = 'Amyloid-beta precursor protein' and Ligand = 'BDBM116257'
TargetAmyloid-beta precursor protein(Human)
Novartis Pharma

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 116257BDBM116257(US8637508, 34 | US10035794, Example 34 | US1068328...)
Affinity DataIC50: 3nMAssay Description:Inhibition of wild type human APP751 expressed in CHO cells assessed as reduction in amyloid beta(1 to 40 residues) levelMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2023
Entry Details Article
PubMed
TargetAmyloid-beta precursor protein(Human)
Novartis Pharma

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 116257BDBM116257(US8637508, 34 | US10035794, Example 34 | US1068328...)
Affinity DataIC50: 3nMAssay Description:Inhibition of wild type APP751 (unknown origin) expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2023
Entry Details Article
PubMed
TargetAmyloid-beta precursor protein(Human)
Novartis Pharma

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 116257BDBM116257(US8637508, 34 | US10035794, Example 34 | US1068328...)
Affinity DataIC50: 3nMAssay Description:Inhibition of wild type human APP751 expressed in CHO cells assessed as reduction in amyloid beta42 levelMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2023
Entry Details Article
PubMed
TargetAmyloid-beta precursor protein(Human)
Novartis Pharma

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 116257BDBM116257(US8637508, 34 | US10035794, Example 34 | US1068328...)
Affinity DataIC50: 4nMAssay Description:Inhibition of wild type human APP751 expressed in CHO cells assessed as reduction in amyloid beta40 levelMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2023
Entry Details Article
PubMed