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Found 1 Enz. Inhib. hit(s) with Target = 'Amyloid-beta precursor protein' and Ligand = 'BDBM455356'
TargetAmyloid-beta precursor protein(Homo sapiens (Human))
Hoffmann-La Roche

US Patent
LigandPNGBDBM455356(8-(4-Fluorophenyl)-N4,5,5-trimethyl-N2-((1R,5S,8s)...)
Affinity DataEC50:  35nMAssay Description:Human neuroglioma H4 cells overexpressing human APP695 with the Swedish double mutation (K595N/M596L) were plated at 30,000 cells/well/100 μl in...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent