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Found 5 Enz. Inhib. hit(s) with Target = 'Amyloid-beta precursor protein' and Ligand = 'BDBM50163996'
TargetAmyloid-beta precursor protein(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50163996(4-(4-Chloro-benzenesulfonyl)-4-(2-methoxy-phenyl)-...)
Affinity DataEC50:  1.03E+3nMAssay Description:In vitro inhibition of amyloid precursor protein 695 activity in CHO cells expressing human APPMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAmyloid-beta precursor protein(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50163996(4-(4-Chloro-benzenesulfonyl)-4-(2-methoxy-phenyl)-...)
Affinity DataEC50:  530nMAssay Description:In vitro reduction of Swedish NL mutant amyloid precursor protein activity expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAmyloid-beta precursor protein(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50163996(4-(4-Chloro-benzenesulfonyl)-4-(2-methoxy-phenyl)-...)
Affinity DataEC50:  640nMAssay Description:In vitro elevation of beta C-terminal fragment (Ct-99) in CHO cells expressing mutant Swedish NL human APPMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAmyloid-beta precursor protein(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50163996(4-(4-Chloro-benzenesulfonyl)-4-(2-methoxy-phenyl)-...)
Affinity DataEC50:  3.50E+3nMAssay Description:In vitro effective concentration against beta amyloid protein 40 in ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAmyloid-beta precursor protein(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50163996(4-(4-Chloro-benzenesulfonyl)-4-(2-methoxy-phenyl)-...)
Affinity DataEC50:  5.00E+3nMAssay Description:In vitro effective concentration against beta amyloid protein 42 in ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed