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Found 3 Enz. Inhib. hit(s) with Target = 'Apoptosis regulator Bcl-2' and Ligand = 'BDBM50181876'
TargetApoptosis regulator Bcl-2(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50181876(CHEMBL371861 | N-(4'-fluoro-biphenyl-4-carbonyl)-3...)
Affinity DataKi:  433nMAssay Description:Binding affinity to Bcl2 by fluorescence polarization assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetApoptosis regulator Bcl-2(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50181876(CHEMBL371861 | N-(4'-fluoro-biphenyl-4-carbonyl)-3...)
Affinity DataIC50:  93nMAssay Description:Binding affinity to Bcl2 by fluorescent polarization assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetApoptosis regulator Bcl-2(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50181876(CHEMBL371861 | N-(4'-fluoro-biphenyl-4-carbonyl)-3...)
Affinity DataIC50:  6.30E+3nMAssay Description:Inhibitory activity against Bcl-XL in presence of HSA3 from 1% human serumMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed