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Found 4 Enz. Inhib. hit(s) with Target = 'Aromatase' and Ligand = 'BDBM50421840'
TargetAromatase(Homo sapiens (Human))
Janssen Research Foundation

Curated by ChEMBL
LigandPNGBDBM50421840(MDL-18962 | PLOMESTANE)
Affinity DataKi:  4nMAssay Description:In vitro inhibition of Cytochrome P450 19A1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAromatase(Homo sapiens (Human))
Janssen Research Foundation

Curated by ChEMBL
LigandPNGBDBM50421840(MDL-18962 | PLOMESTANE)
Affinity DataKi:  6.20nMAssay Description:Binding affinity(KI) for formation of reversible enzyme-ligand complex with human placental aromatase (PL2)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAromatase(Homo sapiens (Human))
Janssen Research Foundation

Curated by ChEMBL
LigandPNGBDBM50421840(MDL-18962 | PLOMESTANE)
Affinity DataKi:  15nMAssay Description:Binding affinity for human placental microsome Cytochrome P450 19A1 by nonlinear regression analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAromatase(Homo sapiens (Human))
Janssen Research Foundation

Curated by ChEMBL
LigandPNGBDBM50421840(MDL-18962 | PLOMESTANE)
Affinity DataIC50:  56nMAssay Description:Inhibition of human placental microsome Cytochrome P450 19A1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed