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Found 2 Enz. Inhib. hit(s) with Target = 'Ataxin-1' and Ligand = 'BDBM50187686'
TargetAtaxin-1(Homo sapiens (Human))
Boehringer Ingelheim International

US Patent
LigandPNGBDBM50187686(CHEMBL3828074 | US10526329, Compound 2 | US1107261...)
Affinity DataIC50:  5nMAssay Description:5 nM recombinant ATX (Cayman Chemicals) was supplemented to 50 mM Tris buffer (pH 8.0) containing 3 mM KCl, 1 mM CaCl2, 1 mM MgCl2 0.14 mM NaCl, and ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetAtaxin-1(Homo sapiens (Human))
Boehringer Ingelheim International

US Patent
LigandPNGBDBM50187686(CHEMBL3828074 | US10526329, Compound 2 | US1107261...)
Affinity DataIC50:  245nMAssay Description:Preparation and Treatment. Stock Solution Preparation. A 10 mM DMSO stock solution was formulated for each compound. A 30 mM DMSO stock solution was ...More data for this Ligand-Target Pair
In DepthDetails US Patent