Affinity DataKi: 1.40E+3nM ΔG°: -33.4kJ/moleT: 2°CAssay Description:In vitro kinase assay using recombinant Aurora A purified from Sf9 cells was incubated at room temperature with substrate, and test compounds in the ...More data for this Ligand-Target Pair
Affinity DataIC50: 1.40E+3nMAssay Description:Inhibition of aurora A kinaseChecked by AuthorMore data for this Ligand-Target Pair
Affinity DataKd: 590nMAssay Description:Binding constant for AURKA kinase domainMore data for this Ligand-Target Pair
Affinity DataKd: 590nMpH: 7.4 T: 2°CAssay Description:Kinase inhibitors are a new class of therapeutics with a propensity to inhibit multiple targets. The biological consequences of multi-kinase activity...More data for this Ligand-Target Pair
Affinity DataKd: 400nMAssay Description:Binding constant for AURKA kinase domainMore data for this Ligand-Target Pair