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Found 3 Enz. Inhib. hit(s) with Target = 'Aurora kinase B' and Ligand = 'BDBM50277679'
TargetAurora kinase B(Homo sapiens (Human))
Vertex Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50277679(CHEMBL484006 | N-(4-(4-(4-tert-butylpiperazin-1-yl...)
Affinity DataKi:  0.800nMAssay Description:Inhibition of Aurora-B by time dependent kinetic studyMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAurora kinase B(Homo sapiens (Human))
Vertex Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50277679(CHEMBL484006 | N-(4-(4-(4-tert-butylpiperazin-1-yl...)
Affinity DataKi:  11nMAssay Description:Inhibition of Aurora-BMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAurora kinase B(Homo sapiens (Human))
Vertex Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50277679(CHEMBL484006 | N-(4-(4-(4-tert-butylpiperazin-1-yl...)
Affinity DataIC50:  11nMAssay Description:Inhibition of aurora B kinaseChecked by AuthorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed