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Found 3 Enz. Inhib. hit(s) with Target = 'B-cell lymphoma 6 protein' and Ligand = 'BDBM50606282'
TargetB-cell lymphoma 6 protein(Homo sapiens)
The Institute Of Cancer Research

Curated by ChEMBL
LigandPNGBDBM50606282(CHEMBL5204505 | US20230287003, Example 12p)
Affinity DataIC50:  1.5nMAssay Description:Inhibition of N-terminal thioredoxin-His6 tagged human BCL6 BTB domain (5 to 129 residues) expressed in Escherichia coli BL21-AI incubated for 2 hrs ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetB-cell lymphoma 6 protein(Homo sapiens)
The Institute Of Cancer Research

Curated by ChEMBL
LigandPNGBDBM50606282(CHEMBL5204505 | US20230287003, Example 12p)
Affinity DataIC50:  4.57nMAssay Description:Each 15 μL HTRF reaction in a 384-well black Proxiplate (Perkin Elmer) contained 1 nM Trx-6×His-BCL6 (in house-produced, human BCL6 BTB domain c...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetB-cell lymphoma 6 protein(Homo sapiens)
The Institute Of Cancer Research

Curated by ChEMBL
LigandPNGBDBM50606282(CHEMBL5204505 | US20230287003, Example 12p)
Affinity DataEC50:  2.70nMAssay Description:Degradation of BCL6 in human OCI-Ly1 cells incubated for 2 hrs by MSD assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed