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Found 2 Enz. Inhib. hit(s) with Target = 'Bcl-2-like protein 1' and Ligand = 'BDBM31406'
TargetBcl-2-like protein 1(Homo sapiens (Human))
University Of Maryland

Curated by ChEMBL
LigandPNGBDBM31406(terphenyl scaffold, 14)
Affinity DataKi:  114nMAssay Description:Inhibition of fluorescein-labeled 16-mer Bak peptide binding to Bcl-xL (unknown origin) by fluorescence polarization assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBcl-2-like protein 1(Homo sapiens (Human))
University Of Maryland

Curated by ChEMBL
LigandPNGBDBM31406(terphenyl scaffold, 14)
Affinity DataKi:  114nM ΔG°:  -39.6kJ/molepH: 7.4 T: 2°CAssay Description:Fluorescence polarization experiments were conducted on a Photon Technology International instrument using a 0.3 cm path length cuvette. Spectra were...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed