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Found 6 Enz. Inhib. hit(s) with Target = 'Bcl-2-like protein 1' and Ligand = 'BDBM50067354'
TargetBcl-2-like protein 1(Homo sapiens (Human))
Shandong University

Curated by ChEMBL
LigandPNGBDBM50067354(CHEMBL3401826)
Affinity DataKi:  570nMAssay Description:Inhibition of Bcl-xL (unknown origin) by fluorescence polarization assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBcl-2-like protein 1(Homo sapiens (Human))
Shandong University

Curated by ChEMBL
LigandPNGBDBM50067354(CHEMBL3401826)
Affinity DataKi:  660nMAssay Description:Competitive binding affinity to Bcl-XL (unknown origin) preincubated for 30 mins followed by 5-FAM-Bid-BH3 peptide addition measured after 20 mins by...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBcl-2-like protein 1(Homo sapiens (Human))
Shandong University

Curated by ChEMBL
LigandPNGBDBM50067354(CHEMBL3401826)
Affinity DataKi:  720nMAssay Description:Inhibition of Bcl-XL (unknown origin) using 5-FAM-Bid-BH3 as substrate preincubated for 30 mins before substrate addition measured after 20 mins by f...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBcl-2-like protein 1(Homo sapiens (Human))
Shandong University

Curated by ChEMBL
LigandPNGBDBM50067354(CHEMBL3401826)
Affinity DataKi:  810nMAssay Description:Inhibition of N-terminal FAM-labeled Bid-BH3 peptide binding to Bcl-XL (unknown origin) preincubated for 30 mins followed by N-terminal FAM-labeled B...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBcl-2-like protein 1(Homo sapiens (Human))
Shandong University

Curated by ChEMBL
LigandPNGBDBM50067354(CHEMBL3401826)
Affinity DataKi:  1.20E+3nMAssay Description:Inhibition of 5-FAM-Bid-BH3 peptide binding to Bcl-XL (unknown origin) pre-incubated for 30 mins followed by further incubation with 5-FAM-Bid-BH3 pe...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBcl-2-like protein 1(Homo sapiens (Human))
Shandong University

Curated by ChEMBL
LigandPNGBDBM50067354(CHEMBL3401826)
Affinity DataKi:  1.30E+3nMAssay Description:Inhibition of 5-FAM-tagged Bid-BH3 peptide binding to Bcl-XL (unknown origin) by fluorescence polarization assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed