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Found 3 Enz. Inhib. hit(s) with Target = 'Bcl-2-like protein 1' and Ligand = 'BDBM50181873'
TargetBcl-2-like protein 1(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50181873(CHEMBL383229 | N-[4-(4,4-dimethylpiperidin-1-yl)be...)
Affinity DataKi:  19nMAssay Description:Binding affinity to Bcl-XL by fluorescence polarization assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBcl-2-like protein 1(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50181873(CHEMBL383229 | N-[4-(4,4-dimethylpiperidin-1-yl)be...)
Affinity DataKi:  652nMAssay Description:Binding affinity to Bcl-XL in 1% human serum by fluorescence polarization assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBcl-2-like protein 1(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50181873(CHEMBL383229 | N-[4-(4,4-dimethylpiperidin-1-yl)be...)
Affinity DataIC50:  79nMAssay Description:Inhibition of FITC-labeled Bak BH3 peptide binding to His6-tagged GST-fused Bcl-xL (unknown origin) expressed in Escherichia coli BL21 preincubated f...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed