Compile Data Set for Download or QSAR
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Found 2 Enz. Inhib. hit(s) with Target = 'Bcl-2-like protein 11 [51-76]/Induced myeloid leukemia cell differentiation protein Mcl-1 [171-327]' and Ligand = 'BDBM605307'
LigandPNGBDBM605307(US11667652, Example 102 | US11667652, Example 111)
Affinity DataIC50:  0.0260nMAssay Description:Inhibition of the MCL1 and Bim interaction was measured in the following AlphaLISA assay.Recombinant human MCL1 protein (C-terminal 6×His Tagged MCL1...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
LigandPNGBDBM605307(US11667652, Example 102 | US11667652, Example 111)
Affinity DataIC50:  0.211nMAssay Description:Inhibition of the MCL1 and Bim interaction was measured in the following AlphaLISA assay.Recombinant human MCL1 protein (C-terminal 6×His Tagged MCL1...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent