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Found 4 Enz. Inhib. hit(s) with Target = 'Beta-2 adrenergic receptor' and Ligand = 'BDBM50092645'
TargetBeta-2 adrenergic receptor(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50092645((R)-N-(4-(2-(2-hydroxy-2-(pyridin-3-yl)ethylamino)...)
Affinity DataIC50:  670nMAssay Description:Displacement of [125]I-cyanopindolol from human recombinant beta2 adrenergic receptor after 1 hr by scintillation counting methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-2 adrenergic receptor(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50092645((R)-N-(4-(2-(2-hydroxy-2-(pyridin-3-yl)ethylamino)...)
Affinity DataIC50:  2.30E+3nMAssay Description:Binding affinity was evaluated on chinese hamster ovary (CHO) cells expressing the cloned human beta-2 adrenergic receptor in the presence of [125I]-...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-2 adrenergic receptor(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50092645((R)-N-(4-(2-(2-hydroxy-2-(pyridin-3-yl)ethylamino)...)
Affinity DataIC50:  2.30E+3nMAssay Description:Displacement of [125I]cyanopindolol from human beta 2 adrenergic receptor expressed in CHO cells at 10 uM after 3 to 4 hrs by scintillation counterMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-2 adrenergic receptor(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50092645((R)-N-(4-(2-(2-hydroxy-2-(pyridin-3-yl)ethylamino)...)
Affinity DataEC50:  2.40E+3nMAssay Description:In vitro functional efficacy in stimulating increase in cAMP in chinese hamster ovary (CHO) cells expressing the cloned human beta2 receptor.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed