Found 3 Enz. Inhib. hit(s) with Target = 'Beta-secretase 1' and Ligand = 'BDBM149914' 
Affinity DataKi: 64.5nM IC50: 109nMAssay Description:Potency of test compounds were determined by measurement of their inhibition of BACE1 activity toward a fluorescent substrate. Experiments were perfo...More data for this Ligand-Target Pair
Affinity DataKi: 64.5nM ΔG°: -41.0kJ/mole IC50: 109nMpH: 4.4 T: 2°CAssay Description:Test Example 1: Potency of test compounds were determined by measurement of their inhibition of BACE1 activity toward a fluorescent substrate. Experi...More data for this Ligand-Target Pair
Affinity DataIC50: 3.20nMT: 2°CAssay Description:Test Example 3: The potency of compounds against BACE1 activity was determined in a cellular assay of Aβ
production. Human SK-N-BE(2) neuroblas...More data for this Ligand-Target Pair
