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Found
1
Enz. Inhib. hit(s) with Target = 'Beta-secretase 1' and Ligand = 'BDBM223406'
Target
Beta-secretase 1
(Homo sapiens (Human))
Pfizer
US Patent
Ligand
BDBM223406
(US9315520, Comparator 4 | US9605007, Comparator 4)
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Affinity Data
IC50: 9nM
Assay Description:
The BACE1 and BACE2 binding assays measured beta-site amyloid precursor protein-cleaving enzyme (BACE) binding as a decrease in the counts of radioli...
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Details
US Patent
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