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Found 5 Enz. Inhib. hit(s) with Target = 'Beta-secretase 1' and Ligand = 'BDBM394123'
TargetBeta-secretase 1(Homo sapiens (Human))
Fondazione Istituto Itaiano Di Tecnologia

US Patent
LigandPNGBDBM394123(US9975861, 3 | US9975861, 4 | US9975861, 5)
Affinity DataIC50:  8.13E+3nMAssay Description:β-secretase (BACE-1, Sigma-Aldrich) inhibition studies were performed by employing a peptide mimicking APP sequence as substrate (Methoxycoumari...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetBeta-secretase 1(Homo sapiens (Human))
Fondazione Istituto Itaiano Di Tecnologia

US Patent
LigandPNGBDBM394123(US9975861, 3 | US9975861, 4 | US9975861, 5)
Affinity DataIC50:  1.26E+4nMAssay Description:β-secretase (BACE-1, Sigma-Aldrich) inhibition studies were performed by employing a peptide mimicking APP sequence as substrate (Methoxycoumari...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetBeta-secretase 1(Homo sapiens (Human))
Fondazione Istituto Itaiano Di Tecnologia

US Patent
LigandPNGBDBM394123(US9975861, 3 | US9975861, 4 | US9975861, 5)
Affinity DataIC50:  1.60E+4nMAssay Description:Inhibition of C-terminal His-tagged recombinant human BACE-1 expressed in mouse NSO cells using methoxy coumarin Ser-Glu-Val-Asn-Leu-Asp-Ala-Glu-Phe-...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetBeta-secretase 1(Homo sapiens (Human))
Fondazione Istituto Itaiano Di Tecnologia

US Patent
LigandPNGBDBM394123(US9975861, 3 | US9975861, 4 | US9975861, 5)
Affinity DataIC50:  1.61E+4nMAssay Description:Inhibition of human acrosin and control activity being 11.3 umol/min/mgMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetBeta-secretase 1(Homo sapiens (Human))
Fondazione Istituto Itaiano Di Tecnologia

US Patent
LigandPNGBDBM394123(US9975861, 3 | US9975861, 4 | US9975861, 5)
Affinity DataIC50:  1.61E+4nMAssay Description:β-secretase (BACE-1, Sigma-Aldrich) inhibition studies were performed by employing a peptide mimicking APP sequence as substrate (Methoxycoumari...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent