Found 4 Enz. Inhib. hit(s) with Target = 'Beta-secretase 1' and Ligand = 'BDBM400979' 
Affinity DataIC50: 0.275nMAssay Description:Inhibition of BACE1 in mouse primary cortical neuron assessed as reduction in Amyloid-beta level incubated for 24 hrs by sandwich ELISA assayMore data for this Ligand-Target Pair
3D Structure (crystal)Affinity DataIC50: 0.615nMAssay Description:Inhibition of recombinant human BACE1 using (MCA)-S-E-V-N-L-D-A-E-F-R-K(dinitrophenol)-R-R-R-R-NH2 as substrate incubated for 8 hrs by FRET assayMore data for this Ligand-Target Pair
Affinity DataIC50: 0.615nMAssay Description:Serial dilutions of test compounds are prepared as described above. Compounds are further diluted 20× in KH2PO4 buffer. Ten μL of each dilution ...More data for this Ligand-Target Pair
Affinity DataIC50: 0.615nMAssay Description:Inhibition of human BACE1 (1 to 460 residues) expressed in HEK293 cells after 16 to 24 hrs by FRET assayMore data for this Ligand-Target Pair
