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Found 2 Enz. Inhib. hit(s) with Target = 'Beta-secretase 1' and Ligand = 'BDBM50012649'
TargetBeta-secretase 1(Homo sapiens (Human))
Janssen Pharmaceutica

Curated by ChEMBL
LigandPNGBDBM50012649(CHEMBL3261063)
Affinity DataIC50:  240nMAssay Description:Inhibition of recombinant human BACE1 extracellular domain expressed in baculovirus using fluorescence-quenched peptide substrate derived from APP se...More data for this Ligand-Target Pair
TargetBeta-secretase 1(Homo sapiens (Human))
Janssen Pharmaceutica

Curated by ChEMBL
LigandPNGBDBM50012649(CHEMBL3261063)
Affinity DataIC50:  240nMpH: 4.5 T: 2°CAssay Description:Recombinant BACE-1 (extracellular domain, expressed in baculovirus and purified using standard methods) at 0.1 to 10 nM concentrations is incubated w...More data for this Ligand-Target Pair