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Found 2 Enz. Inhib. hit(s) with Target = 'Beta-secretase 1' and Ligand = 'BDBM50216175'
TargetBeta-secretase 1(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50216175(CHEMBL425828 | N-[(1S,2R)-2-amino-1-benzyl-3-metho...)
Affinity DataIC50:  12nMAssay Description:Inhibition of BACE1 by ECL assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-secretase 1(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50216175(CHEMBL425828 | N-[(1S,2R)-2-amino-1-benzyl-3-metho...)
Affinity DataIC50:  173nMAssay Description:Inhibition of BACE1 assessed as effect on soluble APPbeta N-terminal fragment secretion in HEK293T cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed