Compile Data Set for Download or QSAR
maximum 50k data
Found 3 Enz. Inhib. hit(s) with Target = 'Beta-secretase 1' and Ligand = 'BDBM50226447'
TargetBeta-secretase 1(Homo sapiens (Human))
Astrazeneca Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50226447(2-amino-3,6-dimethyl-6-phenyl-5,6-dihydro-3H-pyrim...)
Affinity DataIC50:  2.00E+3nMAssay Description:Inhibition of BACE1 by FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-secretase 1(Homo sapiens (Human))
Astrazeneca Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50226447(2-amino-3,6-dimethyl-6-phenyl-5,6-dihydro-3H-pyrim...)
Affinity DataIC50:  3.80E+3nMAssay Description:Inhibition of human full length BACE1 expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-secretase 1(Homo sapiens (Human))
Astrazeneca Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50226447(2-amino-3,6-dimethyl-6-phenyl-5,6-dihydro-3H-pyrim...)
Affinity DataIC50:  3.80E+3nMAssay Description:Inhibition of BACE1 by IGEN assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed