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Found
1
Enz. Inhib. hit(s) with Target = 'Beta-secretase 1 [1-460]' and Ligand = 'BDBM307708'
Target
Beta-secretase 1 [1-460]
(Homo sapiens (Human))
Astrazeneca
US Patent
Ligand
BDBM307708
(4''-fluoro-6'-(3-fluoropropoxy)-4-[(2H3)methyloxy]...)
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Affinity Data
IC50: 1.22E+3nM
Assay Description:
The cDNA for the soluble part of the human 13-Secretase (AA 1-AA 460) was cloned using the ASP2-Fc10-1-IRES-GFP-neoK mammalian expression vector. The...
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Target Info
PDB
UniProtKB/SwissProt
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Ligand Info
PC cid
PC sid
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Details
US Patent
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