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Found 1 Enz. Inhib. hit(s) with Target = 'Beta-secretase 2' and Ligand = 'BDBM190708'
TargetBeta-secretase 2(Homo sapiens (Human))
Merck Sharp & Dohme

US Patent
LigandPNGBDBM190708(US9181236, 12)
Affinity DataKi:  0.300nM ΔG°:  -55.3kJ/molepH: 5.0 T: 2°CAssay Description:Inhibitor IC50s at purified human autoBACE-2 are determined in a time-resolved endpoint proteolysis assay that measures hydrolysis of the QSY7-EISE...More data for this Ligand-Target Pair
In DepthDetails US Patent