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Found 2 Enz. Inhib. hit(s) with Target = 'Beta-secretase 2' and Ligand = 'BDBM50428343'
TargetBeta-secretase 2(Rattus norvegicus)
Temple University

Curated by ChEMBL
LigandPNGBDBM50428343(CHEMBL2331708)
Affinity DataIC50:  2nMAssay Description:Inhibition of BACE2-mediated TMEM27 cleavage in rat INS-1E cells expressing doxycycline-dependent human full-length TMEM27 by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-secretase 2(Rattus norvegicus)
Temple University

Curated by ChEMBL
LigandPNGBDBM50428343(CHEMBL2331708)
Affinity DataIC50:  2nMAssay Description:Inhibition of BACE2 in rat INS-1E cells assessed as TMEM27 cleavage preincubated for 2 hrs followed by doxycycline addition measured after 46 hrs by ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed