Found 1 Enz. Inhib. hit(s) with Target = 'Bifunctional dihydrofolate reductase-thymidylate synthase' and Ligand = 'BDBM134282' TargetBifunctional dihydrofolate reductase-thymidylate synthase(Cryptosporidium hominis)
University of Connecticut
US Patent
University of Connecticut
US Patent
Affinity DataIC50: 36nMAssay Description:Compounds were evaluated in spectrophotometric enzyme assays using ChDHFR-TS and hDHFR. Inhibition constants (IC50) were measured (see Table 4). The ...More data for this Ligand-Target Pair
