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Found 5 Enz. Inhib. hit(s) with Target = 'Bifunctional epoxide hydrolase 2' and Ligand = 'BDBM50327827'
TargetBifunctional epoxide hydrolase 2(Homo sapiens (Human))
The Regents of The University of California

US Patent
LigandPNGBDBM50327827(1-(4-Nitrophenyl)-3-(1-propionylpiperidin-4-yl)ure...)
Affinity DataIC50:  38nMpH: 7.0Assay Description:IC50 values were determined using a sensitive fluorescent based assay (Anal. Biochem. 2005, 343, 66-75). Cyano(2-methoxynaphthalen-6-yl)methyl trans-...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetBifunctional epoxide hydrolase 2(Homo sapiens (Human))
The Regents of The University of California

US Patent
LigandPNGBDBM50327827(1-(4-Nitrophenyl)-3-(1-propionylpiperidin-4-yl)ure...)
Affinity DataIC50:  38nMAssay Description:Inhibition of human recombinant soluble epoxide hydrolase by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBifunctional epoxide hydrolase 2(Homo sapiens (Human))
The Regents of The University of California

US Patent
LigandPNGBDBM50327827(1-(4-Nitrophenyl)-3-(1-propionylpiperidin-4-yl)ure...)
Affinity DataIC50:  38nMAssay Description:The first step in characterizing the two compounds identified by high throughput screening was to verify that the inhibition was reproducible using f...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetBifunctional epoxide hydrolase 2(Mus musculus (Mouse))
Department Of Entomology And University Of California Davis Cancer Center

Curated by ChEMBL
LigandPNGBDBM50327827(1-(4-Nitrophenyl)-3-(1-propionylpiperidin-4-yl)ure...)
Affinity DataIC50:  97nMAssay Description:Inhibition of mouse recombinant soluble epoxide hydrolase by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBifunctional epoxide hydrolase 2(Mus musculus (Mouse))
Department Of Entomology And University Of California Davis Cancer Center

Curated by ChEMBL
LigandPNGBDBM50327827(1-(4-Nitrophenyl)-3-(1-propionylpiperidin-4-yl)ure...)
Affinity DataIC50:  97nMpH: 7.0Assay Description:IC50 values were determined using a sensitive fluorescent based assay (Anal. Biochem. 2005, 343, 66-75). Cyano(2-methoxynaphthalen-6-yl)methyl trans-...More data for this Ligand-Target Pair
In DepthDetails US Patent