Compile Data Set for Download or QSAR
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Found 2 Enz. Inhib. hit(s) with Target = 'Bifunctional purine biosynthesis protein ATIC' and Ligand = 'BDBM22580'
TargetBifunctional purine biosynthesis protein ATIC(Homo sapiens (Human))
The Scripps Research Institute

Curated by ChEMBL
LigandPNGBDBM22580(47729-M | 5-chloro-2-{5-hydroxy-3-methyl-4-[(E)-2-...)
Affinity DataIC50:  3.30E+3nMAssay Description:Inhibition of human AICAR TfaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBifunctional purine biosynthesis protein ATIC(Homo sapiens (Human))
The Scripps Research Institute

Curated by ChEMBL
LigandPNGBDBM22580(47729-M | 5-chloro-2-{5-hydroxy-3-methyl-4-[(E)-2-...)
Affinity DataIC50:  3.30E+3nMpH: 7.5 T: 2°CAssay Description:The human ATIC enzyme was used for the inhibition assay. The assay buffer was flushed with nitrogen to minimize oxidization of cofactor 10-f-THF. The...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed