Affinity DataEC50: 25nMAssay Description:Preparation of human FXR alpha ligand binding domain: The human FXRalpha LBD was expressed in E. coli strain BL21(DE3) as an N-terminally GST tagged ...More data for this Ligand-Target Pair
Affinity DataEC50: 831nMAssay Description:Determination of a ligand mediated Gal4 promoter driven transactivation to quantify ligand binding mediated activation of FXR was performed as follow...More data for this Ligand-Target Pair
Affinity DataEC50: 25nMAssay Description:Determination of a ligand mediated cofactor peptide interaction to quantify ligand binding to the nuclear receptor FXR was performed as follows.Prepa...More data for this Ligand-Target Pair
Affinity DataEC50: 831nMAssay Description:The cDNA part encoding the FXR ligand binding domain was cloned into vector pCMV-BD (Stratagene) as a fusion to the yeast GAL4 DNA binding domain und...More data for this Ligand-Target Pair