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Found 2 Enz. Inhib. hit(s) with Target = 'Bile acid receptor' and Ligand = 'BDBM50552998'
TargetBile acid receptor(Homo sapiens (Human))
Hiroshima International University

Curated by ChEMBL
LigandPNGBDBM50552998(CHEMBL4783777)
Affinity DataIC50:  0.0900nMAssay Description:Antagonist activity against recombinant human FXR transfected in human HuH-7 cells co-transfected with FRE-luciferase assessed as reduction in CDCA-i...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetBile acid receptor(Homo sapiens (Human))
Hiroshima International University

Curated by ChEMBL
LigandPNGBDBM50552998(CHEMBL4783777)
Affinity DataIC50:  65nMAssay Description:Antagonist activity at recombinant GST-tagged FXR LBD (unknown origin) assessed as inhibition of GW4064-induced Fluorecein-SRC2-2 coactivator peptide...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed