Compile Data Set for Download or QSAR
Report error Found 2 Enz. Inhib. hit(s) with Target = 'Biotin carboxylase' and Ligand = 'BDBM3436'
TargetBiotin carboxylase(Escherichia coli (strain K12))
Pfizer

LigandChemical structure of BindingDB Monomer ID 3436BDBM3436(6-(2,6-dibromophenyl)pyrido[2,3-d]pyrimidine-2,7-d...)
Affinity DataIC50: 1nMpH: 8.0 T: 2°CAssay Description:Assays were performed in 384-well clear bottom plates (Corning; catalog no. 3702), that contained inhibitor solvated in DMSO. To each well of the pla...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2009
Entry Details Article
PubMed
TargetBiotin carboxylase(Pseudomonas aeruginosa (strain ATCC 15692 / PAO1 /...)
Achaogen

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 3436BDBM3436(6-(2,6-dibromophenyl)pyrido[2,3-d]pyrimidine-2,7-d...)
Affinity DataIC50: 180nMAssay Description:Inhibition of recombinant N-terminal His-tagged Pseudomonas aeruginosa PAO1 biotin carboxylase expressed in Escherichia coli Rosetta(DE3) pLysS cells...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/25/2021
Entry Details Article
PubMed