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Found 2 Enz. Inhib. hit(s) with Target = 'Broad substrate specificity ATP-binding cassette transporter ABCG2' and Ligand = 'BDBM50560767'
TargetBroad substrate specificity ATP-binding cassette transporter ABCG2(Homo sapiens (Human))
Rheinische Friedrich-Wilhelms-University Bonn

Curated by ChEMBL
LigandPNGBDBM50560767(CHEMBL4755385)
Affinity DataIC50:  253nMAssay Description:Inhibition of human ABCG2 expressed in MDCK2 cells co-expressing GFP preincubated for 30 mins followed by Hoechst 33342 addition and measured every 6...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetBroad substrate specificity ATP-binding cassette transporter ABCG2(Homo sapiens (Human))
Rheinische Friedrich-Wilhelms-University Bonn

Curated by ChEMBL
LigandPNGBDBM50560767(CHEMBL4755385)
Affinity DataIC50:  516nMAssay Description:Inhibition of human ABCG2 expressed in MDCK2 cells co-expressing GFP preincubated for 15 mins followed by pheophorbideA addition and measured after 2...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed