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Found 6 Enz. Inhib. hit(s) with Target = 'Bromodomain-containing protein 2' and Ligand = 'BDBM50452553'
TargetBromodomain-containing protein 2(Homo sapiens (Human))
St. Jude Children'S Research Hospital

Curated by ChEMBL
LigandPNGBDBM50452553(CHEMBL4202664 | US11028051, Cmpd 54)
Affinity DataIC50:  1.40E+3nMAssay Description:Inhibition of recombinant human BRD2 bromodomain 1 (49 to 170 residues) using biotin labeled peptide substrate preincubated for 15 mins followed by s...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetBromodomain-containing protein 2(Homo sapiens (Human))
St. Jude Children'S Research Hospital

Curated by ChEMBL
LigandPNGBDBM50452553(CHEMBL4202664 | US11028051, Cmpd 54)
Affinity DataIC50:  1.40E+3nMAssay Description:Inhibition of recombinant human BRD2 bromodomain 2 (342 to 460 residues) using biotin labeled peptide substrate preincubated for 15 mins followed by ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetBromodomain-containing protein 2(Homo sapiens (Human))
St. Jude Children'S Research Hospital

Curated by ChEMBL
LigandPNGBDBM50452553(CHEMBL4202664 | US11028051, Cmpd 54)
Affinity DataKd:  74nMAssay Description:Binding affinity to His-tagged BRD2 bromodomain 2 (unknown origin) by SPR assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetBromodomain-containing protein 2(Homo sapiens (Human))
St. Jude Children'S Research Hospital

Curated by ChEMBL
LigandPNGBDBM50452553(CHEMBL4202664 | US11028051, Cmpd 54)
Affinity DataKd:  131nMAssay Description:Binding affinity to BRD2 bromodomain 1 (74 to 194 residues) (unknown origin) by ITCMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetBromodomain-containing protein 2(Homo sapiens (Human))
St. Jude Children'S Research Hospital

Curated by ChEMBL
LigandPNGBDBM50452553(CHEMBL4202664 | US11028051, Cmpd 54)
Affinity DataKd:  36nMAssay Description:Binding affinity to BRD2 bromodomain 2 (348 to 455 residues) (unknown origin) by ITCMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetBromodomain-containing protein 2(Homo sapiens (Human))
St. Jude Children'S Research Hospital

Curated by ChEMBL
LigandPNGBDBM50452553(CHEMBL4202664 | US11028051, Cmpd 54)
Affinity DataKd:  99nMAssay Description:Binding affinity to His-tagged BRD2 bromodomain 1 (unknown origin) by SPR assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed