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Found 3 Enz. Inhib. hit(s) with Target = 'Bromodomain-containing protein 4 [342-460]' and Ligand = 'BDBM543516'
TargetBromodomain-containing protein 4 [342-460](Homo sapiens (Human))
Aptose Biosciences

US Patent
LigandPNGBDBM543516(US11279703, TABLE 6.119 | US11279703, TABLE 6.128 ...)
Affinity DataIC50:  13nMAssay Description:1. Add 20 μl of the diluted compound to each well of the 384-well opti plate2. Tap the plate gently3. Add 10 μl of the enzyme to each well ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In DepthDetails US Patent
TargetBromodomain-containing protein 4 [342-460](Homo sapiens (Human))
Aptose Biosciences

US Patent
LigandPNGBDBM543516(US11279703, TABLE 6.119 | US11279703, TABLE 6.128 ...)
Affinity DataIC50:  73nMAssay Description:1. Add 20 μl of the diluted compound to each well of the 384-well opti plate2. Tap the plate gently3. Add 10 μl of the enzyme to each well ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In DepthDetails US Patent
TargetBromodomain-containing protein 4 [342-460](Homo sapiens (Human))
Aptose Biosciences

US Patent
LigandPNGBDBM543516(US11279703, TABLE 6.119 | US11279703, TABLE 6.128 ...)
Affinity DataIC50:  73nMAssay Description:1. Add 20 μl of the diluted compound to each well of the 384-well opti plate2. Tap the plate gently3. Add 10 μl of the enzyme to each well ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In DepthDetails US Patent