Found 5 Enz. Inhib. hit(s) with Target = 'C-C chemokine receptor type 2' and Ligand = 'BDBM50224496'
TargetC-C chemokine receptor type 2(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research And Development
Curated by ChEMBL
Johnson & Johnson Pharmaceutical Research And Development
Curated by ChEMBL
Affinity DataIC50: 2nMAssay Description:Antagonist activity at CCR2 expressed in THP1 cells assessed as MCP1-induced calcium fluxMore data for this Ligand-Target Pair
TargetC-C chemokine receptor type 2(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research And Development
Curated by ChEMBL
Johnson & Johnson Pharmaceutical Research And Development
Curated by ChEMBL
Affinity DataIC50: 4nMAssay Description:Inhibition of human CCR2More data for this Ligand-Target Pair
TargetC-C chemokine receptor type 2(Mus musculus)
Johnson & Johnson Pharmaceutical Research And Development
Curated by ChEMBL
Johnson & Johnson Pharmaceutical Research And Development
Curated by ChEMBL
Affinity DataIC50: 2.00E+3nMAssay Description:Displacement of [125I]-rat MCP1 from rat CCR2 receptor in monocytesMore data for this Ligand-Target Pair
TargetC-C chemokine receptor type 2(Mus musculus)
Johnson & Johnson Pharmaceutical Research And Development
Curated by ChEMBL
Johnson & Johnson Pharmaceutical Research And Development
Curated by ChEMBL
Affinity DataIC50: 2.00E+3nMAssay Description:Displacement of [125I]-mouse MCP1 from CCR2 in mouse WEHI265.1 cellsMore data for this Ligand-Target Pair
TargetC-C chemokine receptor type 2(Mus musculus)
Johnson & Johnson Pharmaceutical Research And Development
Curated by ChEMBL
Johnson & Johnson Pharmaceutical Research And Development
Curated by ChEMBL
Affinity DataIC50: 2.00E+3nMAssay Description:Displacement of [125I]-mouse MCP1 from CCR2 in mouse peripheral blood monocytesMore data for this Ligand-Target Pair