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Found 3 Enz. Inhib. hit(s) with Target = 'C-C chemokine receptor type 2' and Ligand = 'BDBM50506115'
TargetC-C chemokine receptor type 2(Homo sapiens (Human))
Leiden University

Curated by ChEMBL
LigandPNGBDBM50506115(CHEMBL4463626)
Affinity DataKi:  1.70nMAssay Description:Displacement of [3H]-CCR2-RA-[R] from human CCR2 expressed in human U2OS cells incubated for 2 hrs by scintillation spectrometric methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 2(Homo sapiens (Human))
Leiden University

Curated by ChEMBL
LigandPNGBDBM50506115(CHEMBL4463626)
Affinity DataKi:  1.70nMAssay Description:Displacement of [3H]-CCR2-RA-[R] from human CCR2 expressed in human U2OS cells incubated for 2 hrs by scintillation spectrometric methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 2(Homo sapiens (Human))
Leiden University

Curated by ChEMBL
LigandPNGBDBM50506115(CHEMBL4463626)
Affinity DataIC50:  16nMAssay Description:Antagonist activity at CCR2b in human THP1 cells assessed as inhibition of human MCP1 induced calcium flux by fluo-4 dye based fluorescence assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed