Compile Data Set for Download or QSAR
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Found 3 Enz. Inhib. hit(s) with Target = 'C-C chemokine receptor type 5' and Ligand = 'BDBM50089354'
TargetC-C chemokine receptor type 5(Homo sapiens (Human))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50089354(CHEMBL3577945)
Affinity DataIC50:  2.40nMAssay Description:Inhibition of [125I]MCP1-beta binding to CCR5 in human HT1080 cell membranes incubated for 4 to 6 hrsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 5(Homo sapiens (Human))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50089354(CHEMBL3577945)
Affinity DataIC50:  2.40nMAssay Description:Antagonist activity at CCR5 (unknown origin) expressed in human HT1080 cells assessed as blockade of MIP1beta-binding to receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 5(Homo sapiens (Human))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50089354(CHEMBL3577945)
Affinity DataIC50:  4.30nMAssay Description:Antagonist activity against CCR5 in whole blood (unknown origin) assessed as reduction in CD11b upregulationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed