Compile Data Set for Download or QSAR
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Found 5 Enz. Inhib. hit(s) with Target = 'C-X-C chemokine receptor type 3' and Ligand = 'BDBM50300905'
TargetC-X-C chemokine receptor type 3(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50300905(CHEMBL578192 | N-{(R)-1-[3-(4-Cyano-phenyl)-8-cycl...)
Affinity DataIC50:  0.900nMAssay Description:Displacement of [125I]IP10 from CXCR3 receptor expressed in PBMCMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-X-C chemokine receptor type 3(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50300905(CHEMBL578192 | N-{(R)-1-[3-(4-Cyano-phenyl)-8-cycl...)
Affinity DataIC50:  7.30nMAssay Description:Displacement of [125I]IP10 from CXCR3 receptor expressed in PBMC in presence of human plasmaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-X-C chemokine receptor type 3(Mus musculus)
Amgen

Curated by ChEMBL
LigandPNGBDBM50300905(CHEMBL578192 | N-{(R)-1-[3-(4-Cyano-phenyl)-8-cycl...)
Affinity DataIC50:  13nMAssay Description:Displacement of ITAC from CXCR3 receptor in mouse whole blood assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-X-C chemokine receptor type 3(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50300905(CHEMBL578192 | N-{(R)-1-[3-(4-Cyano-phenyl)-8-cycl...)
Affinity DataIC50:  18.9nMAssay Description:Antagonistic activity to CXCR3 receptor expressed in PBMC assessed as inhibition of ITAC-mediated cell migration in presence of 100% human plasmaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-X-C chemokine receptor type 3(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50300905(CHEMBL578192 | N-{(R)-1-[3-(4-Cyano-phenyl)-8-cycl...)
Affinity DataIC50:  21nMAssay Description:Displacement of ITAC from CXCR3 receptor in human whole blood assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed