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Found 3 Enz. Inhib. hit(s) with Target = 'C-X-C chemokine receptor type 4' and Ligand = 'BDBM50458238'
TargetC-X-C chemokine receptor type 4(Homo sapiens (Human))
Soochow University

Curated by ChEMBL
LigandPNGBDBM50458238(CHEMBL4203703)
Affinity DataIC50:  0.730nMAssay Description:Antagonist activity at CXCR4 in human CD4+ T cells assessed as inhibition of CXCL12-mediated cytosolic calcium level preincubated with compounds foll...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetC-X-C chemokine receptor type 4(Homo sapiens (Human))
Soochow University

Curated by ChEMBL
LigandPNGBDBM50458238(CHEMBL4203703)
Affinity DataIC50:  88nMAssay Description:Antagonist activity at CXCR4 in human HPBALL cells assessed as inhibition of APC-conjugate clone 12G5 antibody signal incubated for 3 hrs by flow cyt...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetC-X-C chemokine receptor type 4(Homo sapiens (Human))
Soochow University

Curated by ChEMBL
LigandPNGBDBM50458238(CHEMBL4203703)
Affinity DataIC50:  88nMAssay Description:Displacement of 12G5-CXCL12 from CXCR4 in human HPBALL cells after 3 hrs by FACS analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed