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Found 4 Enz. Inhib. hit(s) with Target = 'C5a anaphylatoxin chemotactic receptor 1' and Ligand = 'BDBM50376793'
TargetC5a anaphylatoxin chemotactic receptor 1(Homo sapiens (Human))
Johnson & Johnson Prd

Curated by ChEMBL
LigandPNGBDBM50376793(CHEMBL259769)
Affinity DataKi:  8.90nMAssay Description:Displacement of [125I]C5a from human C5a receptor in U937 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC5a anaphylatoxin chemotactic receptor 1(Homo sapiens (Human))
Johnson & Johnson Prd

Curated by ChEMBL
LigandPNGBDBM50376793(CHEMBL259769)
Affinity DataIC50:  100nMAssay Description:Antagonist activity at human C5a receptor in U937 cells assessed as inhibition of anaphylatoxin-induced intracellular calcium mobilizationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC5a anaphylatoxin chemotactic receptor 1(Homo sapiens (Human))
Johnson & Johnson Prd

Curated by ChEMBL
LigandPNGBDBM50376793(CHEMBL259769)
Affinity DataIC50:  100nMAssay Description:Antagonist activity at human C5a receptor in U937 cells assessed as inhibition of anaphylatoxin-induced intracellular calcium mobilizationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC5a anaphylatoxin chemotactic receptor 1(Homo sapiens (Human))
Johnson & Johnson Prd

Curated by ChEMBL
LigandPNGBDBM50376793(CHEMBL259769)
Affinity DataIC50: >1.00E+4nMAssay Description:Antagonist activity at human C5a receptor in U937 cells assessed as inhibition of anaphylatoxin-induced intracellular calcium mobilizationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed