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Found 6 Enz. Inhib. hit(s) with Target = 'CREB-binding protein' and Ligand = 'BDBM188517'
TargetCREB-binding protein(Homo sapiens (Human))
Pfizer

LigandPNGBDBM188517(PF-CBP1)
Affinity DataIC50:  130nMAssay Description:The assay used His-tagged CBP protein, biotinylated histone H4, and detection reagents europium-labeled streptavidin and anti-6His antibody labeled w...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCREB-binding protein(Homo sapiens (Human))
Pfizer

LigandPNGBDBM188517(PF-CBP1)
Affinity DataIC50:  130nMAssay Description:Inhibition of CREBBP (unknown origin) by FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCREB-binding protein(Homo sapiens (Human))
Pfizer

LigandPNGBDBM188517(PF-CBP1)
Affinity DataIC50:  130nMAssay Description:Inhibition of CBP (unknown origin) by FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCREB-binding protein(Homo sapiens (Human))
Pfizer

LigandPNGBDBM188517(PF-CBP1)
Affinity DataIC50:  190nMAssay Description:Displacement of biotinylated ligand from CBP (unknown origin) by TR-FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCREB-binding protein(Homo sapiens (Human))
Pfizer

LigandPNGBDBM188517(PF-CBP1)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of Halo-tagged histone H3.3 binding to NanoLuc luciferase conjugated CBP (unknown origin) expressed in HEK293 cells after overnight incuba...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCREB-binding protein(Homo sapiens (Human))
Pfizer

LigandPNGBDBM188517(PF-CBP1)
Affinity DataKd:  190nMAssay Description:Experiments were performed using recombinant CBP and BRD4 bromodomainsusing the procedure reported recently (Hett et al., 2015).More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed