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Found 2 Enz. Inhib. hit(s) with Target = 'Calpain-1 catalytic subunit' and Ligand = 'BDBM23866'
TargetCalpain-1 catalytic subunit(Sus scrofa (pig))
University of Tennessee Health Science Center

LigandPNGBDBM23866(MDL28170 | Z-Val-Phe-CHO | benzyl N-[(1S)-2-methyl...)
Affinity DataKi:  10nM ΔG°:  -45.2kJ/molepH: 7.4 T: 2°CAssay Description:Assays were initiated by addition of CaCl2, and the increase in fluorescence (ex @370 nm, em @440 nm) was monitored. MDL28170 and buffer with 2% DMSO...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCalpain-1 catalytic subunit(Homo sapiens (Human))
Ewha Womans University

LigandPNGBDBM23866(MDL28170 | Z-Val-Phe-CHO | benzyl N-[(1S)-2-methyl...)
Affinity DataIC50:  100nMpH: 7.5 T: 2°CAssay Description:Inhibition of µ-calpain was assayed in the reaction buffer (50 mM Tris-HCl, 50 mM NaCl, 1 mM EDTA, 1 mM EGTA and 5 mM β-mercaptoethanol, pH...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed