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Found 4 Enz. Inhib. hit(s) with Target = 'Cannabinoid receptor 1' and Ligand = 'BDBM50005908'
TargetCannabinoid receptor 1(Homo sapiens (Human))
Arena Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50005908(CHEMBL3234707 | US9062004, 14 | US9670216, 14 4-Br...)
Affinity DataKi:  7.41E+3nMAssay Description:Displacement of [3H]-CP55940 from human CB1 receptor expressed in HEK293 cells after 90 mins by liquid scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 1(Homo sapiens (Human))
Arena Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50005908(CHEMBL3234707 | US9062004, 14 | US9670216, 14 4-Br...)
Affinity DataIC50:  7.41E+3nMT: 2°CAssay Description:Plasma membranes prepared from HEK 293 EBNA cells transfected with human CB1 or CB2 cannabinoid receptors (3.7 or 3.3 pmol/mg protein, receptor conce...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetCannabinoid receptor 1(Homo sapiens (Human))
Arena Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50005908(CHEMBL3234707 | US9062004, 14 | US9670216, 14 4-Br...)
Affinity DataIC50:  7.41E+3nMAssay Description:Plasma membranes prepared from HEK 293 EBNA cells transfected with human CB1 or CB2 cannabinoid receptors (3.7 or 3.3 .mu.mol/mg protein, receptor co...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetCannabinoid receptor 1(Mus musculus (Mouse))
Arena Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50005908(CHEMBL3234707 | US9062004, 14 | US9670216, 14 4-Br...)
Affinity DataEC50:  820nMAssay Description:Agonist activity at CB1 receptor in Swiss Webster mouse vas deferens assessed as inhibition of electrically-stimulated muscle contractionMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed