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Found 25 Enz. Inhib. hit(s) with Target = 'Carbonic anhydrase 1' and Ligand = 'BDBM10855'
TargetCarbonic anhydrase 1(Homo sapiens (Human))
Kochi Medical School

LigandPNGBDBM10855(2-aminobenzene-1-sulfonamide | CHEMBL6705 | US1017...)
Affinity DataKi:  4.54E+4nM ΔG°:  -24.8kJ/molepH: 7.5 T: 2°CAssay Description:An Applied Photophysics stopped-flow instrument has been used for assaying the CA-catalyzed CO2 hydration activity. Phenol red has been used as indic...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 1(Homo sapiens (Human))
Kochi Medical School

LigandPNGBDBM10855(2-aminobenzene-1-sulfonamide | CHEMBL6705 | US1017...)
Affinity DataKi:  4.54E+4nMAssay Description:Inhibition of human CA1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 1(Homo sapiens (Human))
Kochi Medical School

LigandPNGBDBM10855(2-aminobenzene-1-sulfonamide | CHEMBL6705 | US1017...)
Affinity DataKi:  4.54E+4nMAssay Description:Inhibition of human recombinant carbonic anhydrase 1 preincubated for 15 mins by CO2 hydration stopped-flow assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 1(Homo sapiens (Human))
Kochi Medical School

LigandPNGBDBM10855(2-aminobenzene-1-sulfonamide | CHEMBL6705 | US1017...)
Affinity DataKi:  4.54E+4nMAssay Description:Inhibitory activity against human carbonic anhydrase I (CA1)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 1(Homo sapiens (Human))
Kochi Medical School

LigandPNGBDBM10855(2-aminobenzene-1-sulfonamide | CHEMBL6705 | US1017...)
Affinity DataKi:  4.54E+4nMAssay Description:Inhibition of recombinant human carbonic anhydrase-1 by stopped flow CO2 hydrase assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 1(Homo sapiens (Human))
Kochi Medical School

LigandPNGBDBM10855(2-aminobenzene-1-sulfonamide | CHEMBL6705 | US1017...)
Affinity DataKi:  4.54E+4nMAssay Description:Inhibition of human recombinant CA1 by stopped-flow CO2 hydration assayChecked by AuthorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 1(Homo sapiens (Human))
Kochi Medical School

LigandPNGBDBM10855(2-aminobenzene-1-sulfonamide | CHEMBL6705 | US1017...)
Affinity DataKi:  4.54E+4nMpH: 7.5Assay Description:Inhibition of human carbonic anhydrase I by spectrophotometry at pH 7.5More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 1(Homo sapiens (Human))
Kochi Medical School

LigandPNGBDBM10855(2-aminobenzene-1-sulfonamide | CHEMBL6705 | US1017...)
Affinity DataKi:  4.54E+4nMpH: 7.5Assay Description:Inhibition of human recombinant carbonic anhydrase 1 at pH 7.5 by stopped flow CO2 hydration assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 1(Homo sapiens (Human))
Kochi Medical School

LigandPNGBDBM10855(2-aminobenzene-1-sulfonamide | CHEMBL6705 | US1017...)
Affinity DataKi:  4.54E+4nMAssay Description:Inhibition of human recombinant carbonic anhydrase 1 after 15 mins by stopped flow CO2 hydration assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 1(Homo sapiens (Human))
Kochi Medical School

LigandPNGBDBM10855(2-aminobenzene-1-sulfonamide | CHEMBL6705 | US1017...)
Affinity DataKi:  4.54E+4nMAssay Description:Inhibition of human carbonic anhydrase I (CAI)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 1(Homo sapiens (Human))
Kochi Medical School

LigandPNGBDBM10855(2-aminobenzene-1-sulfonamide | CHEMBL6705 | US1017...)
Affinity DataKi:  4.54E+4nMAssay Description:Inhibitory activity against human cloned carbonic anhydrase isozyme I by esterase assay method.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 1(Homo sapiens (Human))
Kochi Medical School

LigandPNGBDBM10855(2-aminobenzene-1-sulfonamide | CHEMBL6705 | US1017...)
Affinity DataKi:  4.54E+4nMAssay Description:Inhibition of cloned isozyme, human carbonic anhydrase IMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 1(Homo sapiens (Human))
Kochi Medical School

LigandPNGBDBM10855(2-aminobenzene-1-sulfonamide | CHEMBL6705 | US1017...)
Affinity DataKi:  4.54E+4nMAssay Description:Inhibitory activity against human carbonic anhydrase I (hCA I) by using esterase assay methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 1(Homo sapiens (Human))
Kochi Medical School

LigandPNGBDBM10855(2-aminobenzene-1-sulfonamide | CHEMBL6705 | US1017...)
Affinity DataKi:  4.54E+4nMAssay Description:Inhibitory activity against human cloned carbonic anhydrase isozyme I (hCA I, cytosolic form).More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 1(Homo sapiens (Human))
Kochi Medical School

LigandPNGBDBM10855(2-aminobenzene-1-sulfonamide | CHEMBL6705 | US1017...)
Affinity DataKi:  4.54E+4nMAssay Description:Inhibitory activity against human recombinant carbonic anhydrase I (CA1)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 1(Homo sapiens (Human))
Kochi Medical School

LigandPNGBDBM10855(2-aminobenzene-1-sulfonamide | CHEMBL6705 | US1017...)
Affinity DataKi:  4.54E+4nMAssay Description:Inhibitory activity against Human carbonic anhydrase IMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 1(Homo sapiens (Human))
Kochi Medical School

LigandPNGBDBM10855(2-aminobenzene-1-sulfonamide | CHEMBL6705 | US1017...)
Affinity DataKi:  4.54E+4nMAssay Description:Ki value against human carbonic anhydrase I (hCA I)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 1(Homo sapiens (Human))
Kochi Medical School

LigandPNGBDBM10855(2-aminobenzene-1-sulfonamide | CHEMBL6705 | US1017...)
Affinity DataKi:  4.54E+4nMAssay Description:Inhibition of human recombinant CA1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 1(Homo sapiens (Human))
Kochi Medical School

LigandPNGBDBM10855(2-aminobenzene-1-sulfonamide | CHEMBL6705 | US1017...)
Affinity DataKi:  4.54E+4nMAssay Description:Ki value against human carbonic anhydrase IMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 1(Homo sapiens (Human))
Kochi Medical School

LigandPNGBDBM10855(2-aminobenzene-1-sulfonamide | CHEMBL6705 | US1017...)
Affinity DataKi:  4.54E+4nMAssay Description:Inhibition of human recombinant cytosolic isozyme CA I by stopped-flow CO2 hydrase methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 1(Homo sapiens (Human))
Kochi Medical School

LigandPNGBDBM10855(2-aminobenzene-1-sulfonamide | CHEMBL6705 | US1017...)
Affinity DataKi:  4.54E+4nMAssay Description:Inhibition of human carbonic anhydrase I (CAI)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 1(Homo sapiens (Human))
Kochi Medical School

LigandPNGBDBM10855(2-aminobenzene-1-sulfonamide | CHEMBL6705 | US1017...)
Affinity DataKi:  4.54E+4nMAssay Description:Inhibition of human recombinant CA1 by stopped-flow CO2 assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 1(Homo sapiens (Human))
Kochi Medical School

LigandPNGBDBM10855(2-aminobenzene-1-sulfonamide | CHEMBL6705 | US1017...)
Affinity DataKi:  4.54E+4nMAssay Description:Inhibition of human recombinant CA1 by stopped-flow CO2 hydrase assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 1(Homo sapiens (Human))
Kochi Medical School

LigandPNGBDBM10855(2-aminobenzene-1-sulfonamide | CHEMBL6705 | US1017...)
Affinity DataKi:  4.54E+4nMAssay Description:An Applied Photophysics stopped-flow instrument has been used for assaying the CA-catalyzed CO2 hydration activity. Phenol red has been used as indic...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 1(Homo sapiens (Human))
Kochi Medical School

LigandPNGBDBM10855(2-aminobenzene-1-sulfonamide | CHEMBL6705 | US1017...)
Affinity DataIC50:  295nMAssay Description:Compounds which are CAIs are well known in the art, see for example, Pastorekova et al, Journal of Enzyme Inhibition and Medicinal Chemistry, 19(3), ...More data for this Ligand-Target Pair
In DepthDetails US Patent