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Found 9 Enz. Inhib. hit(s) with Target = 'Carbonic anhydrase 2' and Ligand = 'BDBM50308986'
TargetCarbonic anhydrase 2(Homo sapiens (Human))
Dumlupinar University

LigandPNGBDBM50308986(2,4-Dichloro-5-sulphamoylbenzoate (2) | CHEMBL5908...)
Affinity DataIC50:  60nMAssay Description:The carbonic anhydrase activity was assayed by following the hydration of CO2 according to the method described by Wilbur and Anderson [Wilbur et al....More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 2(Homo sapiens (Human))
Dumlupinar University

LigandPNGBDBM50308986(2,4-Dichloro-5-sulphamoylbenzoate (2) | CHEMBL5908...)
Affinity DataIC50:  75nMAssay Description:The method for determination of the Ki values is described elsewhere [Landolfi et al., J. Pharmacol. Toxicol. Methods, 38:169-172; Bülbül et al., J. ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 2(Homo sapiens (Human))
Dumlupinar University

LigandPNGBDBM50308986(2,4-Dichloro-5-sulphamoylbenzoate (2) | CHEMBL5908...)
Affinity DataIC50:  100nMpH: 7.4Assay Description:The carbonic anhydrase activity was assayed by following the change in absorbance at 348 nm of the 4-nitrophenylacetate (NPA) to the 4-nitrophenylate...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 2(Homo sapiens (Human))
Dumlupinar University

LigandPNGBDBM50308986(2,4-Dichloro-5-sulphamoylbenzoate (2) | CHEMBL5908...)
Affinity DataIC50:  140nMpH: 7.4Assay Description:The carbonic anhydrase activity was assayed by following the change in absorbance at 348 nm of the 4-nitrophenylacetate (NPA) to the 4-nitrophenylate...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 2(Homo sapiens (Human))
Dumlupinar University

LigandPNGBDBM50308986(2,4-Dichloro-5-sulphamoylbenzoate (2) | CHEMBL5908...)
Affinity DataIC50:  150nMAssay Description:The carbonic anhydrase activity was assayed by following the hydration of CO2 according to the method described by Wilbur and Anderson [Wilbur et al....More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 2(Homo sapiens (Human))
Dumlupinar University

LigandPNGBDBM50308986(2,4-Dichloro-5-sulphamoylbenzoate (2) | CHEMBL5908...)
Affinity DataIC50:  157nMAssay Description:The method for determination of the Ki values is described elsewhere [Landolfi et al., J. Pharmacol. Toxicol. Methods, 38:169-172; Bülbül et al., J. ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 2(Homo sapiens (Human))
Dumlupinar University

LigandPNGBDBM50308986(2,4-Dichloro-5-sulphamoylbenzoate (2) | CHEMBL5908...)
Affinity DataIC50:  220nMAssay Description:Inhibition of human erythrocytes CA2 by Lineweaver-Burke analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 2(Homo sapiens (Human))
Dumlupinar University

LigandPNGBDBM50308986(2,4-Dichloro-5-sulphamoylbenzoate (2) | CHEMBL5908...)
Affinity DataIC50:  290nMAssay Description:Inhibition of esterase-activity of human erythrocytes CA2 by spectrophotometryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 2(Homo sapiens (Human))
Dumlupinar University

LigandPNGBDBM50308986(2,4-Dichloro-5-sulphamoylbenzoate (2) | CHEMBL5908...)
Affinity DataIC50:  300nMAssay Description:Inhibition of hydratase-activity of human erythrocytes CA2 by CO2-hydration methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed